Ivermectin is a medication that has been used for decades to treat various parasitic infections in humans, including onchocerciasis (river blindness), lymphatic filariasis, and strongyloidiasis. However, it has recently gained attention for its potential use in treating COVID-19, although its effectiveness and safety for this purpose are still being researched and debated.
When it comes to the dosage of ivermectin for humans, it’s crucial to understand that the dosage can vary significantly depending on the specific condition being treated, as well as the individual’s weight, age, and other health factors.
For approved uses:
- Onchocerciasis (River Blindness): The typical dose is 150 mcg/kg of body weight, taken orally as a single dose. This dose may be repeated every 6 to 12 months as necessary.
- Strongyloidiasis: The typical dose is 200 mcg/kg of body weight, taken orally as a single dose. This dose may be repeated in 2 weeks if necessary.
- Lymphatic Filariasis: The typical dose is 150 mcg/kg of body weight, taken orally as a single dose, in combination with albendazole. This dose may be repeated every 6 to 12 months as necessary.
For COVID-19 ( investigational use ):
There is ongoing research into the use of ivermectin for COVID-19, and various studies have used different dosages. Some studies have used doses as low as 12 mg once daily for 5 days, while others have used higher doses such as 24 mg once daily for 5 days or even 400 mcg/kg of body weight as a single dose.
Important Considerations:
- Consult a healthcare provider: It is essential to consult with a qualified healthcare provider before taking ivermectin or any medication, especially if it’s for an off-label use like COVID-19.
- Prescription is required: Ivermectin requires a prescription in many countries, and it should only be taken under the guidance of a healthcare professional due to the risk of side effects and interactions with other medications.
- Potential side effects: Common side effects of ivermectin include diarrhea, nausea, dizziness, and abdominal pain. More severe side effects can occur, especially when taken inappropriately high doses.
- Overdose risk: High doses of ivermectin can lead to serious side effects, including severe neuromuscular effects, seizures, and coma.
Given the complexity of ivermectin dosing and the potential for serious side effects, especially when not used as directed by a healthcare provider, it’s critical to approach its use with caution and under professional guidance. Always follow the recommended dosage and consult with a healthcare provider to ensure safe and effective treatment.