Fluconazole 100 Mg

Fluconazole 100 mg is a dosage strength of the antifungal medication fluconazole, which is commonly used to treat various fungal infections. Fluconazole belongs to the class of triazole antifungals and works by inhibiting the synthesis of ergosterol, a critical component of fungal cell membranes. By disrupting the cell membrane, fluconazole effectively kills the fungal cells, providing relief from the infection.

Indications for Use

Fluconazole 100 mg is indicated for the treatment of several types of fungal infections, including:

1. Vaginal Candidiasis: Fluconazole is effective in treating vaginal yeast infections caused by Candida species.
2. Oropharyngeal Candidiasis: Fluconazole can be used to treat oral thrush, a fungal infection that occurs in the mouth and throat.
3. Esophageal Candidiasis: Fluconazole is used to treat fungal infections of the esophagus, which can cause difficulty swallowing and chest pain.
4. Cryptococcal Meningitis: Fluconazole is used to treat fungal meningitis caused by Cryptococcus neoformans, which can be life-threatening if left untreated.
5. Coccidioidomycosis: Fluconazole can be used to treat fungal infections caused by Coccidioides immitis, which can affect the lungs, skin, and other organs.

Administration and Dosage

The recommended dosage of fluconazole 100 mg can vary depending on the type and severity of the fungal infection being treated. Typically, the dosage is as follows:

• Vaginal Candidiasis: A single dose of 150 mg is usually recommended.
• Oropharyngeal Candidiasis: The usual dosage is 100 mg once daily for 7-14 days.
• Esophageal Candidiasis: The recommended dosage is 100 mg once daily for 14-21 days.
• Cryptococcal Meningitis: The initial dosage is 400 mg on the first day, followed by 200 mg once daily for 10-12 weeks.
• Coccidioidomycosis: The recommended dosage is 100-400 mg once daily for 6-12 months.

Contraindications and Warnings

Fluconazole 100 mg is contraindicated in patients with known hypersensitivity to fluconazole or other azole antifungals. Additionally, caution should be exercised when using fluconazole in patients with:

• Liver Disease: Fluconazole can cause liver damage, and patients with pre-existing liver disease should be monitored closely.
• Kidney Disease: Fluconazole can cause kidney damage, and patients with pre-existing kidney disease should be monitored closely.
• Pregnancy and Breastfeeding: Fluconazole should be used with caution in pregnant and breastfeeding women, as it can pass into the fetus or baby.

Side Effects

Common side effects of fluconazole 100 mg include:

• Nausea and Vomiting
• Diarrhea
• Abdominal Pain
• Headache
• Dizziness
• Rash

Less common but more serious side effects can include:

• Liver Damage
• Kidney Damage
• Allergic Reactions
• Seizures

It is essential to consult a healthcare professional if any side effects occur or if the infection does not improve with treatment.